Semaphorins: Receptor and Intracellular Signaling Mechanisms

This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by a family of proteins called the semaphorins. Originally these protein were identified as "axon guidance cues" important for the formation of nerve tracts but now it is realized that semaphorins subserve several distinct functions in a multitude of organ systems.

This book summarizes our knowledge and makes it available as a useful and comprehensive tool for the scientific community. It covers the entire semaphorin field from neurosciences to cardiovascular research and beyond, detailing all the latest techniques and results. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems. The book will be of interest to people working in the field as well as those who work in other fields of science and would like to learn more about semaphorins and associated signaling mechanisms.